Under the microscope: Looking at B.C.'s wastewater surveillance for viruses

1 month_ago 19

British Columbia·New

Scientists accidental they anticipation investigating wastewater for pathogens, which gained prominence during the COVID-19 pandemic successful B.C., continues and helps amended pass the nationalist of emerging threats going forward.

Scientists are acrophobic that aboriginal probe and backing is being chopped back

Akshay Kulkarni · CBC News

· Posted: Mar 17, 2025 10:00 AM EDT | Last Updated: 7 minutes ago

A idiosyncratic   wearing a purple mitt  connected  1  manus  holds up   a vessel  of murky brownish  liquid.

A sewage illustration is seen successful this record photo. B.C.'s wastewater surveillance programme gained prominence during the COVID-19 pandemic, and scientists accidental they anticipation the enactment continues. (Rick Bowmer/The Associated Press)

Testing wastewater for diseases and viral enactment gained prominence during the pandemic, but scientists are acrophobic that backing for specified enactment could beryllium threatened.

Monitoring wastewater for pathogens — and adjacent illicit and medicine drugs — was astir for decades earlier the pandemic, but the method of estimating microorganism levels gained nationalist attraction astatine the highest of the pandemic when it was unclear however overmuch illness was circulating.

The B.C. Centre for Disease Control (BCCDC) stepped up its surveillance and present regularly monitors the wastewater from astir the state to gauge microorganism levels — not conscionable for COVID-19, but besides for influenza and respiratory syncytial microorganism (RSV).

Scientists accidental they anticipation Canada continues to money that work. Ontario ended its COVID-19 wastewater surveillance program successful July 2024 and a probe vacuum is looming southbound of the border.

People with COVID-19 shed SARS-CoV-2 microorganism successful their poop, whether they person symptoms oregon not. Samples of untreated assemblage wastewater supply utile accusation astir whether cases are expanding oregon decreasing. <br><br>Learn astir wastewater surveillance: <a href="https://t.co/ATeJY4FBJY">https://t.co/ATeJY4FBJY</a> <a href="https://t.co/KwZatpSu5T">pic.twitter.com/KwZatpSu5T</a>

&mdash;@CDCofBC

"Before the pandemic, determination was nary regular usage of wastewater data," said Natalie Prystajecky, an biology microbiologist astatine the BCCDC. "That was this immense innovation that occurred due to the fact that of the pandemic."

Prystajecky has worked connected the wastewater programme since the pandemic began successful 2020, and has been monitoring the different respiratory pathogens since 2022.

A achromatic  pistillate   wearing a bluish  garment  smiles.

Natalie Prystajecky present studies aggregate pathogens arsenic portion of the wastewater surveillance programme astatine the BCCDC. She says she's present looking to survey gut pathogens similar salmonella. (CBC)

Humans who declaration COVID-19 volition shed traces of SARS-CoV-2 — the virus that causes the disease — in their feces, and authorities cod aggregate samples per week to amusement trends successful microorganism loads implicit time.

During the Omicron question of the pandemic successful precocious 2021, B.C.'s investigating capableness became overwhelmed — which is erstwhile the wastewater monitoring dashboard became 1 of the much reliable sources of accusation astir microorganism levels successful the community.


"That information became disposable publicly, and it seemed similar the nationalist truly ... was capable to recognize it and relied connected it," Prystajecky said.

The researcher said that the wastewater surveillance program, which expanded extracurricular Metro Vancouver during the pandemic, is present successful a spot wherever researchers tin amended woody with the adjacent pandemic.

How does it work?

Jesse Shapiro, an subordinate prof of microbiology and immunology astatine McGill University, was among galore researchers who analyzed wastewater samples shipped to labs astir the country.

There, helium says a "bunch of chemistry" is done to instrumentality wastewater from trial tubes and ore it into substances that tin past beryllium sequenced to find familial code.


The microbiologist said that, initially, trying to find the signals for a caller microorganism similar SARS-CoV-2 would person been similar uncovering a needle successful a haystack.

But arsenic scientists gained amended investigating methods, it became a batch much outgo effectual to observe however overmuch microorganism was circulating and what variants were much dominant.

"An vantage of wastewater surveillance is that it tin beryllium incredibly effective, due to the fact that those laboratory methods are really not precise costly astatine all," the prof said.

Three radical   wearing laboratory  coats look   astatine  trial  tubes successful  a lab.

Graduate students look astatine COVID-19 successful wastewater samples connected March 23, 2022 astatine a schoolhouse laboratory astatine the Ohio State University successful Columbus, Ohio. (Patrick Orsagos/The Associated Press)

Future of wastewater surveillance

Shapiro was portion of the Coronavirus Variants Rapid Response Network (CoVaRR-Net), a cross-Canada web of researchers that was funded by the Canadian Institutes of Health Research and produced a fig of studies connected COVID-19 and different viruses.

However, the backing for the programme ended this month, and different wastewater surveillance programs person been removed successful provinces similar Ontario.

WATCH | Ontario ends wastewater investigating program: 

Health curate defends Ontario's determination to extremity its wastewater investigating program

Ontario Health Minister Sylvia Jones said the state accrued wastewater surveillance during the COVID-19 pandemic, but is present returning to a "normal authorities of affairs."

"We are seeing less programs similar this continuing to beryllium run," Prystajecky acknowledged.

"[In] these adjacent stages, we're starting to truly deliberation astir the champion and astir meaningful mode of utilizing wastewater surveillance."

Prystajecky said she is present utilizing the information to look astatine gut-based pathogens similar norovirus and salmonella, arsenic good arsenic antimicrobial absorption among pathogens.

Shapiro said he hopes that Canada is moving toward a aboriginal wherever there's much unfastened information sharing based connected wastewater surveillance, with academics connected manus to construe the information and marque nationalist wellness recommendations.

"It's incredibly important for things similar surveillance of vertebrate flu, H5N1, emerging pathogens, things that are spreading," helium said. "If you don't look, you won't find it."

A oversea  of bluish  membranes punctuated by yellowish  circles and sticks.

Jesse Shapiro with McGill University says that wastewater surveillance is precise important to observe emerging diseases similar avian flu, which tin dispersed to humans. (CDC/NIAID/The Associated Press)

As the U.S. government moves to chopped backing to the National Institute of Health and Center for Disease Control, which are some heavy progressive with wastewater surveillance, Shapiro said there's an accidental for Canada to capable the looming void and fund subject probe much broadly.

"I deliberation it's really rather indispensable for Canada and different countries to measurement up and not conscionable beryllium wholly reliant connected the U.S. for this benignant of thing," helium said.

ABOUT THE AUTHOR

Akshay Kulkarni is an award-winning writer who has worked astatine CBC British Columbia since 2021. Based successful Vancouver, helium is astir funny successful data-driven stories. You tin email him astatine [email protected].

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With files from Courtney Dickson

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